Curriculum frameework

Academic Training in Applied Microbiology (MIC804)

Course Summary: Development of skills for preparing projects, dissertations and theses in Microbiology, with an emphasis on the writing process and the preparation of presentations. The teacher-student support will be carried out individually or in small groups, with the aim of better exploring the potential and individuality of the students. The bibliography to be used will be evaluated on a case-by-case basis, depending on the student's research project.

Bibliography: Development of skills for preparing projects, dissertations and theses in Microbiology, with an emphasis on the writing process and the preparation of presentations. The teacher-student support will be carried out individually or in small groups, with the aim of better exploring the potential and individuality of the students. The bibliography to be used will be evaluated on a case-by-case basis, depending on the student's research project.

Course load: 60 hours
Credits: 4
Coordinators: Program Advisors

Virology Applied to Medicine and Public Health (MIC807)

Course summary: Study of viruses, with a focus on medicine and public health

Course load: 30 hours
Credits: 2
Coordinator:

Seminars in Microbiology (MIC808)

Syllabus: Aims to guide the graduate student in reading, interpreting and presenting general topics in Microbiology, in areas of study that do not coincide with their thesis subject.

Bibliography: Articles related to the seminar of the week.

Workload: 30 hours
Credits: 02
Coordinator: Prof. Aristóteles Goes Neto

Special Topics in Microbiology: Methods in Microbiology (MIC815)

Syllabus: Execution of basic methods in microbiology including the three major areas: virology, bacteriology and mycology. Preparation of materials, culture media and important reagents for the microbiology laboratory, cultivation of microorganisms, cell cultivation, quantification of microorganisms and cells, extraction of genetic material from microorganisms, detection of antigens and neutralizing antibodies and polymerase chain reaction.

Bibliography: Current scientific articles on the practical procedures covered.

Workload: 60 hours
Credits: 4
Coordinators:
Prof. Elisabeth Neumann
Prof. Susana Johann
Prof. Jordana Grazziela Alves Coelho dos Reis
Prof. Vera Lúcia Santos
Prof. Luiz Henrique Rosa
Prof. Rodrigo Araújo Lima Rodrigues
Prof. Luiz Macedo de Farias
Prof. Viviane de Souza Alves
Postdoctoral student Gustavo José Cota de Freitas
Postdoctoral student Sílvia Helena Sousa Pietra Pedroso
Postdoctoral student Graciele Alves Cunha de Menezes

Epidemiology and Control of Hospital Infections (MIC819)

Program: Study of epidemiological concepts applied to healthcare-associated infections. Infection control techniques.

Bibliography: Current scientific articles on the topic of each class.

Working hours: 45 hours
Credits: 3
Coordinators:

Bacteriology of Anaerobes (MIC824)

Course summary: Introduction to the study of anaerobic bacteria (obligate anaerobes), including their biology and systematics (Archaea and Bacteria domains), ecological aspects in nature and in hosts, and biotechnological importance. Main groups of human and veterinary medical importance and pathogenesis of diseases involving anaerobic bacteria. Isolation and culture-dependent and culture-independent methods for identification and characterization of anaerobic bacteria, including those for determining the susceptibility profile to antimicrobial drugs.

Bibliography: Current scientific review articles published in foreign journals.

Workload:60 hours
Credits: 4
Coordinators:
Prof. Jacques Nicoli
Prof. Luiz de Macêdo Farias
Prof. Paula Prazeres Magalhães

Special Topics in Microbiology - Presentations of Academic-Scientific Papers (MIC827)

Syllabus: Topics of interest to students, not included in other disciplines, raised by the evaluation of professional practice, presented in the form of seminars and also involving research activities. The Board will define the program every semester, which will be taught by visiting professors or with their participation.

Bibliography: National and international articles and subjects related to Microbiology

Workload: 15 hours
Credits: 1
Coordinator:
Prof. Sílvia Beleza de Moura
Prof. Mônica Larucci Vieira

Biotechnology-Fermentation (MIC832)

Syllabus: Study of microorganisms and their biotechnological applications, with a focus on fermentation technology.

Bibliography: Current scientific articles on the topic of each class.

Duration: 60 hours
Credits: 4
Coordinator: Prof. Carlos Augusto Rosa

Special Topics in Microbiology: Vaccines and Antivirals (MIC835)

Syllabus:

Course Hours: 30hs
Credits: 2
Coordinator:
Prof. Jordana Grazziela Alves Coelho dos Reis
Prof. Flávio Guimarães da Fonseca

Special Topics in Microbiology: Emerging Microorganisms - Fungi (MIC835)

Syllabus: This course will address emerging microorganisms associated with infections and processes of importance in public, environmental and technological health. This semester will address fungi as emerging and reemerging microorganisms in the context of One Health, emphasizing their environmental, animal and human importance. Phytopathogenic fungi, human and animal pathogens, and fungi of great biotechnological interest will be addressed, as well as the methodologies used to study the mechanisms of adaptation to the environment and the host, resistance to antifungals and current therapeutic strategies.

Special Topics in Microbiology: Biostatistics applied to research (MIC835)

Course summary: To introduce and develop in graduate students the ability to plan, plot and interpret data obtained in their research. Initially, the course will focus on recognizing variables (continuous, categorical and ordinal), position and dispersion measures, categorization of data types and analysis of dispersion patterns. The main statistical analyses used in the area of biology will be presented and then students will practice choosing the most appropriate statistical test and graphical representation for each type of variable (weight, survival, microbial load, cytokines, growth curve, etc.). Finally, the course will also develop the skills to construct graphical representations for different types of results. During the course, the data analysis software Prism and Stata will be used.

Workload: 30
Credits: 02
Coordinators:
Prof. Daniel de Assis Santos
Postdoctoral Fellow Gustavo José Cota de Freitas

Special Topics in Microbiology: Resistance genes: theoretical and bioinformatics aspects (MIC835)

Course outline: The course will have two main blocks. A first block focused on microbiological aspects such as: definition and basic concepts of resistance genes, genetic adaptations of microorganisms and development of resistance in the presence of antifungals. After the first part, there will be a second part focused on aspects involving bioinformatics and application of tools to obtain the resistome of an organism. At this point, there will be an introduction to the command line (Linux), explanation of what databases are and where to find resistance genes, conserved protein domains and characterization of resistomes of microorganisms. During the course, there will be practical application to predict resistomes using the HMMER3 software.
Didactics: Expository and practical class in the HMMER3 software. Workload Assessment: Seminars on resistomes carried out by the students.

Course load: 30 hours
Credits: 2
Coordinators:
Prof. Daniel de Assis Santos
Prof. Daniel Santana de Carvalho
Prof. Ludmila Gouveia Eufrasio

Special Topics in Microbiology - Microbiology applied to the conservation of cultural heritage (MIC835)

Syllabus: Main microbial representatives associated with biological, chemical and physical deterioration; Basic concepts of microbial ecology and metabolism; Biodeterioration, biodegradation and microbial bioreceptivity (rock, paper, fabric, wood, painting) in indoor and outdoor environments. Approach to classical and molecular techniques for microbial isolation and identification associated with cultural heritage; Definition and application of microbial growth control techniques according to the origin and composition of the work of art; Approach to microbiological and environmental monitoring methods in indoor environments; Preventive microbiological conservation in museums, churches, technical reserves and libraries; Assessment of potential risks to the health of professionals involved in the presence of microorganisms.

Course Hours: 30
Credits: 02
Coordinators:
Prof. Maria Aparecida de Resende Stoianoff
Postdoctoral Fellow Douglas Boniek Silva Navarro

Topics in Microbiology: R Environment - Application in biostatistics (MIC835A)

Course summary: Course summary: The course aims to contextualize the practical application of biostatistical methods, using the R language for analysis and interpretation of biological data.

Bibliography:

Course load: 30
Credits: 2
Coordinators:
Prof. Nalu Teixeira de Aguiar Peres
Postdoctoral student Grace Santos Tavares Avelar

Special Topics in Microbiology: Mycology: isolation and identification techniques (MIC835B)

Course summary: To train students in techniques for isolation, characterization and identification of filamentous fungi from environmental samples. The course will cover theoretical and practical methods, including molecular and morphological techniques, for the identification of fungi. Principles of collection and processing of environmental samples (soil and plants).
Techniques for the isolation of filamentous fungi and methods of cultivation in the laboratory. Macro and micromorphological characteristics for presumptive identification. Evaluation and description of colonies for initial characterization purposes. Methods for counting Colony Forming Units (CFU). Techniques for purification and preservation of fungal cultures. DNA extraction steps and preparation for molecular analysis. Use of molecular fingerprinting techniques such as PCR with primer (GTG)5] for grouping and genetic identification. Analysis of microculture and PCR results.
Compilation and interpretation of results for the preparation of scientific reports.

Special Topics in Microbiology - Personal development plan and related skills in the microbiologist's career (MIC835B)

Course summary: Assessment of skills, interests and values in relation to short, medium and long-term career goals. Understanding and exploring possibilities for professional careers in the area of microbiology and related fields. Self-assessment and establishment of goals and a personal development plan. Identification and strengthening of skills and competencies (communication among peers; management and leadership, responsible research conduct) aiming at strengthening the professional career.

Bibliographies
https://myidp.sciencecareers.org
https://collections.plos.org/collection/ten-simple-rules/
Articles and various websites with free access

Workload: 30
Credits: 02
Coordinator: Betânia Paiva Drumond

Special Topics in Microbiology - Systematics of MACROfungi (MIC835D)

Syllabus: Historical Development, Classification Systems of Macrofungi. Methods of Study of Macrofungi I: Collection and Preservation (Herbarium and Mycotheque). Methods of Study of Macrofungi II: External and Internal Morphology (Macroscopy, Microscopy). Methods of Study of Macrofungi III: DNA Sequencing of Non-Coding and Coding Genomic Biomarker Regions. Ecological Groups and Geographic Distribution. Phylogeny and Evolution of Macrofungi. Characterization and Description of Species (including New Ones) in an Integrated Way: Morphologically and Molecularly

Bibliography: Mycology: Diversity, Morphology, Ökologie und Evolution der Pilze. Springer, 2022

Workload: 15 hours
Credits: 1
Coordinator: Prof. Aristóteles Goes Neto

Special Topics in Microbiology: Viruses with Importance to Human Health (MIC835D)

Syllabus: Study of the main families of viruses involved in the processes of infection in humans. Aspects related to viral particles, their multiplication in cells and dissemination in the host will be addressed. Epidemiology and control methods will also be discussed.

Hours: 30
Credits: 02
Coordinator: Prof. Erna Geessien Kroon

Special Topics in Microbiology - Molecular modeling applied to research in (MIC835D)

Course summary:To present and develop different molecular modeling techniques, such as protein prediction and modeling, selection and/or characterization of molecular targets, construction of ligands, and evaluation of target-ligand or protein-protein interactions (molecular docking). Methods that do not require prior knowledge and can be applied in the three major areas: bacteriology, mycology, and virology will be used. The following topics will be addressed: use of different tools, interpretation of results, and graphical representation of data, both in a gradual and sequential manner. The design will proceed from the choice of a target of interest and/or modeling of a target, to the evaluation of the interaction of possible inhibitors, substrates, or protein-protein. During the course, protein modeling servers (AlphaFold2 and SWISS-MODEL) and structure characterization (FTSite and FTMap) will be used, in addition to the construction of ligands (Discovery Studio), evaluation of target-ligand interactions or docking (GOLD), protein-protein interaction servers (HDOCK), in addition to data visualization and graphical representation of results (PyMOL).

Bibliography:

Workload:30 hours
Credits:2
Coordinator:
Prof. Jônatas Santos Abrahão
Postdoctoral Fellow Matheus Sá Magalhães Serafim

Special Topics in Microbiology - Biotechnology in Microbiology (MIC835E)

Syllabus:
Hours: 30 hours
Credits: 2
Coordinator: Prof. Flavio Guimarães da Fonseca

Special Topics in Microbiology: Resistance genes: theoretical and bioinformatics aspects (MIC835F)

Syllabus: The discipline has two main blocks. The first block focuses on microbiological aspects such as: definition and basic concepts of resistance genes, genetic adaptations of microorganisms and development of resistance in the presence of antifungals. The second part focuses on aspects involving bioinformatics and the application of tools to obtain the resistome of an organism. At this point, there will be an introduction to the command line (Linux), an explanation of what databases are and where to find resistance genes, conserved protein domains and characterization of resistomes of microorganisms. During the course, there will be practical application to predict resistomes using the HMMER3 software.

Workload: 30 hours
Credits: 2
Coordinators:
Prof. Daniel de Assis Santtos
Postdoctoral student Daniel Santana de Carvalho
Postdoctoral student Ludamila Gouveia Eufrásio

Special Topics in Microbiology - Probiotics (MIC836)

Syllabus: History and state of the art of the subject of probiotics, from the history, isolation of probiotic strains to clinical trials and their applications in various ecosystems (oral, gastrointestinal, genitourinary, respiratory and cutaneous). In addition, it will address the use of probiotics in humans and other animals and the subject in the era of genomics (genetically modified probiotics and probiogenomics), new generation probiotics, and variations of probiotics (symbiotics, postbiotics and psychobiotics).

Hours: 45
Credits: 03
Coordinator: Prof. Flaviano dos Santos Martins

Special Topics in Microbiology: Emerging Microorganisms: Arboviruses (MIC836)

Syllabus:

Hours: 45hs
Credits: 3
Coordinators:
Jordana Grazziela Alves Coelho dos Reis
Daniele da Glória de Souza
Giliane de Souza Trindade

Special Topics in Microbiology: Emerging Microorganisms: Bacteriology (MIC836)

Syllabus: Study of the morphological, molecular and pathogenicity aspects of the group of gram-negative bacteria. Discussion of virulence factors and resistance mechanisms of enterobacteriaceae, with emphasis on the ESKAPE group.

Bibliography: scientific articles, selected by the students themselves.

Duration: 45 hours
Credits: 3
Coordinators:
Professor Daniele da Glória de Souza
Professor Caio Tavares Fagundes

Special Topics in Microbiology - Innovation, Entrepreneurship and Market in Biotechnology (MIC836)

Course Summary: Innovation. Intellectual Property. Fundraising for R&DI. Entrepreneurship: CANVAS; Business Plan and Pitch. Capital Market. Job Market: Evolution of Professions; Hard Skills vs. Soft Skills. Business Trends and Opportunities in Life Sciences.

Course load: 45hs
Credits: 3
Coordinator: Prof. Junio Cota Silva

Special Topics in Microbiology - Introduction to phylogenetic inferences applied to the study of microorganisms (MIC836A)

Syllabus: Basic concepts of molecular evolution. Nucleic acid sequencing. Biological databases, sequence search by similarity, nucleotide sequence alignment. Data sets and sequence quality analysis. Phylogenetic reconstruction methods: distance methods, parsimony, likelihood and Bayesian analysis, evolutionary models, confidence tests. Recombination and selection analyses. Estimation of evolutionary parameters.

Course load: 45h
Credits: 3
Coordinator: Prof. Betânia Paiva Drumond

Special Topics: Isolation and identification of microorganisms: bases for taxonomy (MIC836B)

Syllabus:The 30-hour discipline MIC836 A aims to specifically address morphological and molecular taxonomy, phylogeny, sequence analysis, evolution and diversity indices of fungi.

Cross-Cutting Topics for Graduate Studies II: Biotechnological applications of the invertebrate model C. elegans. (NAP801)

Syllabus: Syllabus: Biotechnological applications of the invertebrate model C. elegans.

Bibliography: Recent scientific articles on the topic of each class.
Workload: 30
Credits: 2

Cross-Cutting Topics for Graduate Studies II (NAP802)

Syllabus: Course offered by different graduate programs, with the offering managed by the Graduate Support Center (NAPG) of the ICB. The courses have open enrollment for all graduate courses at the ICB-UFMG and allow students to have a cross-cutting education.

Bibliography: Recent scientific articles on the topic of each class.

Workload: 30 hours
Credits: 2
Coordinators: Program advisors